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The most common usage of MPA is in the form of DMPA as a lengthy-acting progestogen-only injectable contraceptive to circumvent pregnancy in Females. It is a particularly successful contraceptive when used with rather substantial doses to circumvent ovulation. MPA is also employed together by having an estrogen in menopausal hormone therapy in postmenopausal Gals to take care of and forestall menopausal signs and symptoms for instance hot flashes, vaginal atrophy, and osteoporosis.[3] It is actually Employed in menopausal hormone therapy particularly to avoid endometrial hyperplasia and cancer that might or else be induced by prolonged unopposed estrogen therapy in Females with intact uteruses.
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Depo-Provera® can be a medicine that you choose to inject into your arm or butt to avoid pregnancy for as much as twelve weeks.
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The FDA endorses that DMPA not be useful for longer than two years, Unless of course there is no practical option technique of contraception, on account of concerns in excess of bone decline.[104] Nevertheless, a 2008 Committee Belief in the American Congress of Obstetricians and Gynecologists (ACOG) advises Health care vendors that issues about bone mineral density reduction should really neither stop the prescription of depo 10 or continuation of DMPA outside of two decades of use.[113]
There are worries a couple of feasible risk of despair and temper adjustments with progestins like MPA, and this has brought about reluctance of some clinicians and women to make use of them.[81][eighty two] Nevertheless, Opposite to extensively-held beliefs, most investigate indicates that progestins don't cause adverse psychological consequences for example depression or panic.
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